Publications

2011-present

  • Ding DC, Wen YT, Tsai RK. Pigment epithelium-derived factor from ARPE19 promotes proliferation and inhibits apoptosis of human umbilical mesenchymal stem cells in serum-free medium. Experimental & Molecular Medicine (2017) 49, e411 (2017) doi:10.1038/emm.2017.219. View full text
  • Kapupara K, Wen YT, Tsai RK & Huang SP. Soluble P-selectin promotes retinal ganglion cell survival through activation of Nrf2 signaling after ischemia injury. Cell Death & Disease (2017) 8, e3172 (2017) doi:10.1038/cddis.2017.566. View full text
  • Huang TL, Wang JK, Pang CY, Tsai RK (2017) Leber’s Hereditary Optic Neuropathy Associated with the m.10197G>A Mutation. J Clin Exp Ophthalmol 8:673. doi: 10.4172/2155-9570.1000673. View full text
  • Acute Zonal Occult Outer Retinopathy (AZOOR): a case report of vision improvement after intravitreal injection of Ozurdex. Kuo YC, Chen N, Tsai RKBMC Ophthalmology (2017) 17:236 DOI 10.1186/s12886-017-0638-5. View full text
  • Wen YT, Tsai RK. The granulocyte colony-stimulating factor (G-CSF) induced stabilization of blood-optic nerve barrier (BOB) in the optic nerve (ON) crush model via PI3K/AKT activation. Investigative Ophthalmol Vis Scie 2017 58(8): 1094-1094.
  • Tsai RK, Wen YT. The roles of autophagy and mTOR in the neuro-protection of optic nerve crush models in rats. Investigative Ophthalmology & Visual Science, 2017, 58(8): 3871-3871.
  • Chang YH, Liu HW, Chu TY, Wen YT , Tsai RK. Cisplatin-Impaired Adipogenic Differentiation of Adipose Mesenchymal Stem Cells1. Cell Transplantation 26 (6):1077-1087. View full text
  • Tsai RK, Lee YC, Wang JH, Huang TL. Increased Risk of Stroke in Patients With Nonarteritic Anterior Ischemic Optic Neuropathy: A Nationwide Retrospective Cohort Study Reply. AMERICAN JOURNAL OF OPHTHALMOLOGY. 2017 Mar 1;175:214. View full text 
  • Huang TL, Wen YT, Chang CH, Chang SW, Lin KH, Tsai RKEarly Methylprednisolone Treatment Can Stabilize the Blood-Optic Nerve Barrier in a Rat Model of Anterior Ischemic Optic Neuropathy (rAION). Invest Ophthalmol Vis Sci 2017 58:1628-1636. View full text
  • Georgiou T ,Wen YT, Chang CH, Kolovos P, Kalogerou M, Prokopiou E, Neokleous A, Huang CT, Tsai RK. Neuroprotective Effects of Omega-3 Polyunsaturated Fatty Acids in a Rat Model of Anterior Ischemic Optic Neuropathy. Invest Ophthalmol Vis Sci 2017;58:1603-1611. (NCBI updating)
  • Wen YT, Huang TL, Huang SP, Chang CH, Tsai RK. Early applications of granulocyte colony-stimulating factor (G-CSF) can stabilize the blood-optic-nerve barrier and ameliorate inflammation in a rat model of anterior ischemic optic neuropathy (rAION). Dis Model Mech 2016;9:1193-1202.2. View full text
  • Tsai MH, Chang CH, Tsai RK, Hong YR, Chuang TH, Fan KT, Peng CW, Wu CY, Hsu WL, Wang LS, Chen LK, Yu HS. Cross-Regulation of Proinflammatory Cytokines by Interleukin-10 and miR-155 in Orientia tsutsugamushi-Infected Human Macrophages Prevents Cytokine Storm. J Invest Dermatol 2016;136:1398-1407. View full text
  • Lee YC, Wang JH, Huang TL, Tsai RK. Increased Risk of Stroke in Patients With Nonarteritic Anterior Ischemic Optic Neuropathy: A Nationwide Retrospective Cohort Study. Am J Ophthalmol 2016;170:183-189.View full text
  • Huang TL, Wen YT, Chang CH, Chang CW, Lin KH, Tsai RK. Efficacy of Intravitreal Injections of Triamcinolone Acetonide in a Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy. Invest Ophthalmol Vis Sci 2016;57:1878-1884. View full text
  • Huang SP, Fang KT, Chang CH, Huang TL, Wen YT, Tsai RK. Autocrine protective mechanisms of human granulocyte colony-stimulating factor (G-CSF) on retinal ganglion cells after optic nerve crush. Exp Eye Res 2016;143:132-140. View full text
  • Chien JY, Sheu JH, Wen ZH, Tsai RK, Huang SP. Neuroprotective effect of 4-(Phenylsulfanyl)butan-2-one on optic nerve crush model in rats. Exp Eye Res 2016;143:148-157. View full text
  • Cheng HC, Huang TL, Lin KJ, Tsai RK, Woung LC, Yen MY, Wang AG. Summary of the Neuro-Ophthalmology Symposium in the 31st Asia-Pacific Academy of Ophthalmology Congress (APAO 2016). Neuroophthalmology 2016;40:251-253. View full text
  • Liu YC, Chen N, Hsu YH, Sheu MM, Tsai RK. Basaloid squamous cell carcinoma of the conjunctiva. Ophthal Plast Reconstr Surg 2015;31:e28-30.View full text
  • Lee CH, Lai PS, Lu YP, Chen HY, Chai CY, Tsai RK, Fang KT, Tsai MH, Hsu CY, Hung CC, Wu DC, Yu HS, Chang CH, Tsai DP. Real-time vascular imaging and photodynamic therapy efficacy with micelle-nanocarrier delivery of chlorin e6 to the microenvironment of melanoma. J Dermatol Sci 2015;80:124-132. View full text
  • Lai YH, Huang SP, Chen SP, Hu PS, Lin SF, Sheu MM, Wang HZ, Tsai RK. A novel gene mutation in a family with X-linked retinoschisis. J Formos Med Assoc 2015;114:872-880. View full text
  • Huang TL, Huang SP, Chang CH, Lin KH, Chang SW, Tsai RK. Protective effects of systemic treatment with methylprednisolone in a rodent model of non-arteritic anterior ischemic optic neuropathy (rAION). Exp Eye Res 2015;131:69-76.View full text
  • Huang TL, Chang CH, Chang SW, Lin KH, Tsai RK. Efficacy of Intravitreal Injections of Antivascular Endothelial Growth Factor Agents in a Rat Model of Anterior Ischemic Optic Neuropathy. Invest Ophthalmol Vis Sci 2015;56:2290-2296. View full text
  • Huang SP, Chien JY, Tsai RK. Ethambutol induces impaired autophagic flux and apoptosis in the rat retina. Dis Model Mech 2015;8:977-987. View full text
  • Huang CT, Chen SP, Tsai RK. The gene mutation in a Taiwanese family with X-linked retinoschisis. Kaohsiung J Med Sci 2015;31:309-314. View full text
  • Chen N, Hsieh HP, Tsai RK, Sheu MM. Eye care services for the populations of remote districts in eastern Taiwan: a practical framework using a Mobile Vision Van Unit. Rural Remote Health 2015;15:3442. View full text
  • Huang TL, Huang SP, Chang CH, Lin KH, Sheu MM, Tsai RK. Protective effects of cerebrolysin in a rat model of optic nerve crush. Kaohsiung J Med Sci 2014;30:331-336. View full text
  • Huang TL, Huang SP, Chang CH, Lin KH, Sheu MM, Tsai RK. Factors influencing the retrograde labeling of retinal ganglion cells with fluorogold in an animal optic nerve crush model. Ophthalmic Res 2014;51:173-178. View full text
  • Huang SP, Tsai RK. Efficacy of granulocyte-colony stimulating factor treatment in a rat model of anterior ischemic optic neuropathy. Neural Regen Res 2014;9:1502-1505. View full text
  • Cheng HC, Tsai RK, Woung LC, Yen MY, Wang AG. Proceedings of the Neuro-ophthalmology Symposium in the 54th Annual Meeting of the Ophthalmological Society of Taiwan, November 30, 2013, Taipei, Taiwan. Neuroophthalmology 2014;38:167-169.View full text
  • Chen N, Huang TL, Hsu YH, Lin HZ, Tsai RK. Orbital Manifestations of Immunoglobulin G4-Related Disease in Bilateral Lacrimal Glands, Optic Nerves, Trigeminal Nerves, and Maxillary Sinuses. Neuroophthalmology 2014;38:24-28. View full text
  • Chang CH, Tsai RK, Tsai MH, Lin YH, Hirobe T. The roles of Frizzled-3 and Wnt3a on melanocyte development: in vitro studies on neural crest cells and melanocyte precursor cell lines. J Dermatol Sci 2014;75:100-108. View full text
  • Chang CH, Huang TL, Huang SP, Tsai RK. Neuroprotective effects of recombinant human granulocyte colony-stimulating factor (G-CSF) in a rat model of anterior ischemic optic neuropathy (rAION). Exp Eye Res 2014;118:109-116. View full text
  • He MS, Sheu MM, Huang ZL, Tsai CH, Tsai RK. Sudden bilateral vision loss and brain infarction following cosmetic hyaluronic acid injection. JAMA Ophthalmol 2013;131:1234-1235. View full report
  • Lin HZ, Pang CY, Chen SP, Tsai RK. Vision improvement in a Taiwanese (Han Chinese) family with Leber’s hereditary optic neuropathy. Kaohsiung J Med Sci 2012;28:679-682. View full text
  • Hsu SY, Ko ML, Linn G, Chang MS, Sheu MM, Tsai RK. Effects of age and disc area on optical coherence tomography measurements and analysis of correlations between optic nerve head and retinal nerve fibre layer. Clin Exp Optom 2012;95:427-431. View full text
  • Fang TC, Pang CY, Chiu SC, Ding DC, Tsai RK. Renoprotective effect of human umbilical cord-derived mesenchymal stem cells in immunodeficient mice suffering from acute kidney injury. PLoS One 2012;7:e46504. View full text
  • Chen YJ, Tsai RK, Wu WC, He MS, Kao YH, Wu WS. Enhanced PKCdelta and ERK signaling mediate cell migration of retinal pigment epithelial cells synergistically induced by HGF and EGF. PLoS One 2012;7:e44937. View full report
  • Chen N, Huang TL, Tsai RK, Sheu MM. Prevalence and causes of visual impairment in elderly Amis aborigines in Eastern Taiwan (the Amis Eye Study). Jpn J Ophthalmol 2012;56:624-630. View full text
  • Tsai RK, He MS, Chen ZY, Wu WC, Wu WS. PKCdelta-dependent signaling mediates ethambutol-induced toxic effects on human retinal pigment cells. Mol Vis 2011;17:1564-1576. View full text
  • Huang TL, Chang CH, Lin KH, Sheu MM, Tsai RK. Lack of protective effect of local administration of triamcinolone or systemic treatment with methylprednisolone against damages caused by optic nerve crush in rats. Exp Eye Res 2011;92:112-119. View full text